Vertex Forward: Our animated video series

colorful collage of scientific line drawings

At Vertex, we believe the most important medicines are those that have a transformative impact for patients. And while drug discovery and development are complicated processes, learning about our approach and the diseases in our pipeline doesn’t have to be. We’re excited to share this animated video series, “Vertex Forward: Illustrating our Scientific Strategy,” where you can see our philosophy and strategy explained.

Illustrating our scientific strategy

illustration of Scientist using pipette

Learn about the Vertex research principles that are the connective thread behind everything we do — from discovering molecules and potential treatment approaches to applying our work in the clinic — and our hopes for the future of our expanding pipeline. 

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Our focus on sickle cell disease

illustration of blood cells

Watch as we illustrate the underlying cause of sickle cell disease (SCD) and our strategy to investigate multiple approaches to hopefully treat those living with SCD.

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Our focus on beta thalassemia

Beta Thalassemia

Check out our illustrated explanation of beta thalassemia’s underyling biology and our work on multiple approaches to hopefully treat those living with beta thalassemia.

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Exploring APOL1-mediated kidney disease

scientific drawing of the kidneys

See how inherited changes in the APOL1 gene can cause severe kidney diseases, including focal segmental glomerulosclerosis (FSGS), and how our scientists are working toward a potential treatment for APOL1-mediated FSGS.

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Diving into type 1 diabetes

type1 diabetes islet cell illustration

Join us in learning about the science behind this chronic metabolic disease and our innovative research into cell therapy approaches for a potential treatment. 

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Innovating in pain research

Illustration of pain signals in synapse

Learn about the manifestations and underlying cause of pain in the body and our investigational program to treat it as we research new mechanisms we hope will selectively inhibit pain signals.

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Our journey in cystic fibrosis

An illustration of a human body showing the lungs and digestive tract with the words "Cystic Fibrosis" displayed

For over two decades, Vertex has been working to discover, research and develop small molecule medicines to treat the underlying cause of cystic fibrosis (CF). Learn more about the disease and how we are committed now more than ever to potentially discovering therapeutic advances for all people living with CF.

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Taking on AATD

Scientific drawing of lungs and liver in human body

Take a few minutes to learn about the inherited lung and liver disease alpha-1 antitrypsin deficiency (AATD), and see how we're using our expertise in protein folding (from our research in cystic fibrosis) as the foundation for our research for a potential treatment for AATD. 

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Navigating Duchenne muscular dystrophy

scientific illustration of boy flexing bicep

Take a few minutes to learn about Duchenne muscular dystrophy (DMD) and see how we're investigating CRISPR gene-editing technology in the hopes of changing precise parts of the DMD gene. 

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