Putting science first

two scientists working at a lab bench

Investing in science
to improve lives

We believe in the promise and potential of science to have a transformative impact for people living with serious diseases. It’s how we create value for patients, families and society as a whole. It’s why we dedicate the vast majority of resources toward innovation, from building teams of top talent to creating a robust toolkit of technologies — all of our efforts are aimed at treating serious diseases. We invest in science so people can live better lives. 

Creating a virtuous cycle

We invest most of our resources back into our research and development engine. 

 

*2021 GAAP figures. Operating expenses defined as R&D + Sales, General and Administrative.


Our strategy in action

 

Female scientist in automation lab

Pioneers in CF research and development 

We discovered, developed and produced the first medicines to target the underlying cause of cystic fibrosis (CF) — the result of more than 20 years of research and development. And we haven’t stopped. We continue to investigate additional potential therapies for all people with CF. 

A Vertex scientist holds several vials in his hand while examining them

Building our toolkit in cell and genetic therapies 

We’re investing in cell and genetic therapies to build an industry leading portfolio of technologies, teams and manufacturing capabilities. We're committed to pushing the scientific envelope by leveraging emerging therapeutic modalities that have the potential to have a transformative impact for patients who are waiting.  

A female Vertex scientist wearing goggles studies a computer monitor

A portfolio approach to development

When we decide to work on a disease, we investigate it from every angle. For example, our sickle cell disease and beta thalassemia programs include advancing our research on a potential one-time gene editing therapy, working to discover and develop potential conditioning regimens with the aim of improving the stem cell transplant process, and exploring potential oral small molecule treatment options.

employees in a meeting

A team sport 

Drug discovery is a team sport. We partner with organizations who are driven to innovate together to solve some of science’s most difficult problems. Our partners share our passion and our goals to better the lives of patients. 

White background